Profile

Abu Gafar Hossion, Ph.D.

Chair of Chemistry, Assistant Professor of Chemistry, Chemical Hygiene Officer
College of Science and Society, Natural Science and Mathematics
(203) 576-4174
Dana Hall, Room 153

Dr. Hossion has a diverse background in education, teaching and research from multiple institutions. He has several experiences in teaching undergraduate students, including a faculty position of Chemistry Professor at Cloud County Community College, Assistant Professor of Chemistry at Fort Hays State University, Chemistry Adjunct Faculty at Haskell Indian Nations University and others. He pursued postdoctoral studies in multidisciplinary research and in interdisciplinary teaching at College of Pharmacy of the University of Oklahoma Health Sciences Center, School of Medicine of the University of Pittsburgh and the University of Kansas, from July 2011 to July 2016.

In 2013, he was awarded the NIH IRACDA fellowship at the University of Kansas to develop undergraduate education and to assist the students from groups underrepresented. He had mentored and trained undergraduate research students at the University of Kansas, Fort Hays State University and Cloud County Community College. In his postdoctoral studies in multidisciplinary research, he discovered a promising cancer treatment of photo-unclick chemistry of visible light controlled release of anticancer drugs via singlet oxygen. He served as reviewer for several Journals including American Chemical Society Journal of Medicinal Chemistry, where he was recognized as an outstanding reviewer in 2013. He is the editor of the book “Vancomycin: Biosynthesis, Clinical Uses and Adverse Effects”. He is serving as an editor of SF Journal of Pharmaceutical and Analytical Chemistry.

Hossion's research interests are in multidisciplinary research at the chemistry/biology interface with an emphasis on the discovery and development of small molecule-based tools that manipulate biological processes and novel therapeutic agents with potential for treatment of human disease.

Dr. Hossion joined the University of Bridgeport in August 2021 and has much enthusiasm to explore the undergraduate chemistry education program. He is currently providing Hands on Research training in multidisciplinary research to the Chemistry minor and Biology major Students College of Science & Society. His current research student at University of Bridgeport accepted to UCONN Chemistry Department REU program 2022. He is collaborating with the mini-grant support at University of Bridgeport

 

 

Ph.D. in majoring Medicinal Chemistry, Okayama University, Japan, 2011

M.S. in majoring Medicinal Chemistry, Okayama University, Japan, 2008

M.S. in Organic Chemistry, Jahangirnagar University, Bangladesh, 2002

B.S. in Chemistry, Jahangirnagar University, Bangladesh, 2001

CHEM-205 Organic Chemistry I

CHEM-206 Organic Chemistry II

CHEM-399-AH Independent Study

Independent Research

CHEM-103 General Chemistry I

CHEM-104 General Chemistry II

CHEM-113 Intro Chemistry

CHEM-114 Intro to Biochem

Selected Peer-Reviewed Publications 
  1. Nagamatsu, T.; Ahmed, S.; Hossion, Abugafar M. L.; and Ohno. S.; “Synthesis of Thieno[3.2-e][1,2,4]triazolo[1,5-c]pyrimidine-3(6H)-ones via their [1,2,4]triazolo[4,3-c]pyrimidine Compounds as New Ring Systems by Dimroth-Type Rearrangement” Heterocycles 2007, 73, 777. DOI: 10.1002/chin.200818153.
  2. Kandahary, R. K.; Hossion, Abugafar M. L.; Ashida, N.; Nagamatsu, T.; “Novel and Facile Synthesis and Evaluation of Antitumor Activities of 6,7-bisaryl-1-(β-D-ribofurnosyl)pteridine-2,4-(1H,3H)-diones”, Heterocycles 2009, 80, 557. DOI: 10.1002/chin.201021199
  3. Hossion, Abugafar M. L.; Islam, R.; Kandahary, R. K.; Nagamatsu, T.; Synthesis and Chemoselective N– and O– Alkylation of Thiadiazolopyridine Nuclosides and Uridines” Synthesis 2009, 16, 2689; DOI: 10.1055/s-0029-1216882.
  4. Hossion, Abugafar M. L.; Otsuka, N.; Kandahary, R. K.; Tsuchiya, T.; Ogawa, W.; Iwado, A.; Zamami, Y.; Sasaki, K.; “Design, Synthesis and Biological Evaluation of a Novel Series of Quercetin Diacylglucosides as Potent Anti-MRSA and Anti-VRE Agents”. Bioorg. Med. Chem.  Lett. 2010, 20, 5349; http://dx.doi.org/10.1016/j.bmcl.2010.02.060.
  5. Sasaki, K.; Tsuchiya, T.; Hossion, Abugafar M. L. Novel flavanone derivative. PCT Int. Pat. Appl. WO 2011013735. 2011; National University Corporation Okayama University, Japan; http://patentscope.wipo.int/search/en/WO2011013735
  6. Rabbani, M. G.; Islam, M. R.; Ahmad, M.; Hossion, Abugafar M. L. “Synthesis of some NH-Derivatives of Ciprofloxacin as Antibacterial and Antifungal Agents”. Bangladesh J. Pharmacol. 2011, 6, 8; DOI: http://dx.doi.org/10.3329/bjp.v6i1.7720.
  7. Hossion, Abugafar M. L.; Zamami, Y.; Kandahary, R. K.; Tsuchiya, T.; Ogawa, W.; Iwado, A.; Sasaki, K.; Quercetin Diacylglycoside Analogues Showing Dual Inhibition of DNA Gyrase and Topoisomerase IV as Novel Antibacterial Agents. J. Med. Chem. 2011. 54, 3686; dx.doi.org/10.1021/jm200010x.
  8. Bio, M;  Rajaputra, P.; Nkepang, G.; Awuah, S. G.;  Hossion, A. M. L. and You, Y. Site-specific and Far-Red Light-Activatable Prodrug of Combretastain A-4 Using Photo-Unclick Chemistry. J.Med.Chem 2013, 56, 3936. http://pubs.acs.org/doi/abs/10.1021/jm400139w
  9. Hossion, A. M. L.; Moses, B.; Nkepang, G.; Awuah, S. and You, Y. Visible light controlled release of anticancer drug through double activation of prodrug. ACS Med. Chem. Lett. 2013, 4, 124.  http://pubs.acs.org/doi/abs/10.1021/ml3003617
  10. Hossion, A. M. L. and Sasaki, K. Novel Quercetin Glycosides as Potent Anti-MRSA and Anti-VRE agents. Recent Pat Antiinfect Drug Discov. 2013, 8, 198. (Special issue 2014) http://www.ncbi.nlm.nih.gov/pubmed/24320230
Patents
  1. Sasaki, K.; Tsuchiya, T.; Hossion, Abugafar M. L. PCT Int. Pat. Appl. WO 2011013735. Novel flavanone derivatives. (National University Corporation Okayama University, Japan) http://www.google.com/patents/US20120202980?cl=ja
  2. You, Youngjae; Moses, Bio; Hossion, Abugafar M. L. PCT Int. Pat. Appl. WO 2013163321 A1. Singlet oxygen-labile linkers and methods of production and use thereof. (University of Oklahoma, Health Sciences Center) http://www.google.com/patents/WO2013163321A1?cl=en